General Terms and Conditions for Ambulanzpartner Soziotechnologie APST GmbH and for the use of the APST platform and the APST mobile applications.

Updated on November 25, 2025

APST – General Terms and Conditions

There is a great need for medical research in the field of neurological diseases, especially amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA) and other neurodegenerative and neuromuscular diseases. This research is crucial for the development of new therapies and the improvement of healthcare for these diseases. An important advance in modern medicine is the active involvement of patients through the structured collection of treatment data and the implementation of treatment-related surveys. APST supports these research efforts by providing a digital research platform and mobile applications that can be used to digitally collect and manage research-related data for medical studies.

1. scope of application

1.1. These General Terms of Use (GTU) apply to the use of the services offered by Ambulanzpartner Soziotechnologie APST GmbH (hereinafter referred to as “APST”) and the use of the APST research platform (hereinafter referred to as “APST platform”) and mobile software applications, including the “ALS app”, “SMA app” and other mobile applications (hereinafter referred to as “APST apps”).

1.2. APST’s services support patients with chronic, serious or rare diseases in participating in medical research projects. Patients are authorized as app users and receive individual user accounts. The legal basis for this is the individual agreements concluded upon conclusion of the contract and these General Terms and Conditions.

1.3. By registering, the patient (or his/her legal representative) agrees to the General Terms and Conditions and the Privacy Policy. APST reserves the right to amend these General Terms and Conditions if necessary, in particular for factual and/or legal reasons, stating these reasons. The amended terms and conditions will be sent to the patient (or his/her legal representative) by e-mail to the e-mail address last communicated to APST and stored on the APST platform one month before they come into force. If the patient has not lodged an objection within 14 days of receiving the e-mail, the amended terms and conditions shall be deemed to have been accepted and shall govern the future contractual relationship between the patient and APST. If the patient (or their legal representative) files an objection, the contract ends in accordance with section 4.2.

1.4. The patient may not transfer the rights and obligations arising from this contract. The assignment of rights is excluded.

2 Subject matter of the contract and services

2.1. APST provides services that serve research, in particular the organization of research and networking between patients, medical partners and scientific institutions. The entirety of these services is referred to as “research organization” and comprises the following components:

• Coordination of the partners involved
• Provision of the necessary participation documents (e.g. questionnaires)
• Provision of the technical requirements for data collection at home or in medical facilities (via APST apps or study software)
• Conducting patient surveys via the APST apps, by telephone or by post
• Coordination of the shipment and analysis of biological samples

The components of the research organization can be used together or individually.

2.2. APST makes the APST platform available to patients for voluntary use. The APST platform is a structured database with an associated digital platform that enables the electronic recording, storage and processing of patient and research-related data as well as the digital support of research processes. The APST platform and the associated applications are software products of APST.

2.3. APST apps are accessed via a combination of personal user name and password. These login details also enable patient authentication for APST apps. The functions of the APST apps, the data collected, the user roles and authorizations as well as the terms of use are described in the privacy policy.

2.4. APST provides patients with apps that allow them to participate in surveys and rate disease symptoms, the progression of symptoms and their experience with treatment.

2.5. APST supports patients or their legal representatives and other users authorized by the patient in using the apps. APST offers a free telephone briefing before the apps are used and, if required, further free, individually agreed training courses.

2.6. With the patient’s consent, their data will be passed on to medical partners for inspection, processing and use. The patient can revoke their original consent at any time with immediate effect without giving reasons. APST ensures that the corresponding declaration of consent complies with all legal requirements, in particular data protection requirements.

2.7. The provision of access requirements (e.g. internet connection and web browser) is not part of the contractual relationship between the patient and APST.

3. conclusion of contract

3.1 The use of the services mentioned in 2.1 and the software of the APST apps requires the conclusion of a user agreement. This contractual relationship is established by providing comprehensive information to the patient and the signing of a declaration of consent by the patient. The following documents will be sent or handed to the patient for this purpose:

• APST’s privacy policy for research coordination and the use of APST apps and other study software for the purpose of data collection, evaluation, aggregation and analysis.
• Declaration of consent to participate in research coordination and to use APSTApps.

The patient fills in the required information (address, e-mail address) on the declaration of consent. By signing the declaration of consent, the patient agrees to these GTC and accepts them. The patient sends the signed declaration of consent by post or e-mail (with the signed document attached) to the following address:

Ambulance partner sociotechnology APST GmbH

Westhafenstr. 1 13353 Berlin

Germany

or e-mail: info@ambulanzpartner.de

After receiving the signed declaration of consent, the patient receives an e-mail with a registration link for the selected applications (“apps”). The patient assigns their own user name and password.

3.2. By concluding the contract, the patient agrees to these General Terms and Conditions and the Privacy Policy. 3.3. The patient assures that the information provided by him/her upon conclusion of the contract is complete and correct. In the event of a breach, APST is entitled to block the patient’s user account immediately.

4. term and termination of the contract

4.1. The contractual relationship is concluded for an indefinite period.

4.2. Both parties can terminate the contract at any time with a notice period of four weeks to the end of the month. Notice of termination must be given in writing or in text form. Ambulanzpartner Soziotechnologie APST GmbH Westhafenstr. 1 13353 Berlin or by e-mail: info@ambulanzpartner.de

4.3 Both contracting parties are entitled to extraordinary termination for good cause, in particular in the event of a material breach of contract which makes the continuation of the contract unreasonable for one of the contracting parties.

4.4 The provisions in Section 2.5 and the patient’s rights arising therefrom remain unaffected.

5 Patient obligations and safety instructions

5.1. The patient is obliged to keep their access data (user name, password) safe and to protect it from unauthorized access by third parties in the same way as valuables. The patient is expressly recommended to use anti-virus, anti-spyware and firewall software as well as the latest versions of their current browser. If the patient uses outdated browser versions, the APST apps may not be displayed correctly. In this case, the patient can obtain information about suitable browsers and their versions from APST.

5.2. The patient undertakes not to publish any illegal content in the APST app or make it accessible to third parties, for example via forums, chat rooms, e-mail or spam. Violations of the contractual restrictions on use entitle APST to take appropriate remedial measures, including blocking the user account. In this case, the patient will be informed immediately of the type, duration, reason and scope of the blocking.

5.3. The accuracy of the data and information provided by the patient influences the value of the contractual services provided by APST. The patient expressly indemnifies APST against all claims for damages by third parties who have relied on the completeness, accuracy and timeliness of the data and information.

6. costs for the use of APST services and software

Use of the APST apps is free of charge for patients and persons authorized by them.

7. data security, consent to data processing, protection of patient data

7.1. APST is subject to the data protection regulations of the Federal Republic of Germany, the European Union (EU-DSGVO) and the Federal Data Protection Act of June 19, 1992 (BDSG). APST is obliged to protect the data of patients and other parties involved on the basis of these provisions.

7.2. APST takes all organizational and technical precautions required by the current state of the art to meet data protection requirements, in particular to protect patient data from unauthorized access by third parties. The transmission of stored data via the World Wide Web from the server to the patient’s computer and vice versa is carried out using the SSL encryption standard.

7.3 The patient expressly agrees to the collection, processing and use of his/her data by APST within the scope of the contractually agreed purposes and by means of a separate data protection declaration.

8. liability

8.1 APST shall be liable without limitation for all damage caused by APST and its legal representatives and/or vicarious agents in cases of intent or gross negligence.

8.2. In the event of slight negligence, APST shall be liable without limitation for damage to life, limb or health caused by APST, its legal representatives and/or vicarious agents. 8.3. Liability under the Product Liability Act remains unaffected.

8.4. Otherwise, APST shall only be liable if a quality guarantee has been given or an essential contractual obligation (cardinal obligation) has been breached. The term “cardinal obligation” refers abstractly to those obligations whose fulfillment is essential for the proper execution of the contract and on whose compliance the patient may regularly rely. In such cases, liability is limited to compensation for foreseeable, typical damages.

9. rights of use

9.1. APST grants the patient a non-exclusive (non-sublicensable and non-transferable) right of use, which is limited to the duration of the contract.

9.2. The patient is only entitled to use the APST apps within the scope of the contractual provisions. The software is not transferred to the patient.

9.3. The patient is not authorized to make the contractual service available to third parties. Access for relatives of the patient or other persons authorized by the patient is excluded. With the patient’s consent, the third party authorized by the patient will receive an e-mail from APST with a registration link for a selected APST app. This person assigns the user name and password themselves. The patient is not authorized to sublet the contractual software.

10. evaluations

10.1 APST provides patients and their authorized representatives with software tools, including APST apps and study-specific platforms, to document and assess the patient’s disease progression. The results of the assessments are published in aggregated form, without naming the patient, on the APST homepage and its subpages. The patient agrees to the following provisions.

10.2. The reviews must be objective and must not contain any illegal content. APST is not liable for the accuracy, quality or completeness of the reviews. APST will remove inappropriate or illegal reviews if there is a clear indication of this.

11. final provisions

11.1 Should any provision of these General Terms and Conditions be or become invalid or void, this shall not affect the validity of the remaining provisions. The invalid or void provision shall be replaced by a valid provision that comes as close as possible to the legal purpose of the invalid or void provision. This also applies to any loopholes in these General Terms and Conditions.

11.2 The law of the Federal Republic of Germany shall apply. The statutory provisions restricting the choice of law and the applicability of mandatory provisions, in particular of the country in which the patient as a consumer has his habitual residence, shall remain unaffected. If the patient is a merchant, a legal entity under public law or a special fund under public law, the registered office of APST shall be the exclusive place of jurisdiction for all disputes arising from the contractual relationship.